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however, substantial cell loss occurs following transplantation (Vadala et al., 2012)

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For instance, non-steroidal anti-inflammatory drugs (NSAIDs) are effective in reducing pain and inflammation but may cause gastrointestinal bleeding, renal damage, and cardiovascular issues with long-term use ( 5.2 Surgical treatments Surgery is the main option for patients with severe symptoms or those who fail non-surgical treatments, including lumbar discectomy and spinal fusion

For systemic or gut-related protocols, the abdominal fat pad at the navel region is used