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In vivo biodistribution and antitumor efficacy in PC-3 tumor models The pharmacokinetics of the intravenously injected ZFPG NPs were assessed in PC-3 tumor-bearing male Balb/c nude mice to reveal their in vivo behaviors

Animals and experimental design SpragueDawley rats (male, 220250 g, 12 weeks old) were obtained from the Animal Housing Unit, Faculty of Veterinary Medicine, Zagazig University, Egypt

10 mg in 1 mL floor of total dose 20 units ( 0.2 mL ) on a 0.3 mL syringe for a 2000 mcg dose

Tissue and urine catecholamines were quantified, as reported [1, 15, 16]

In the serum of patients with ALL, it has been found that copper levels are significantly increased ( Copper forms coordination compounds in liver cells with proteins, amino acids, and other substances