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Widely studied in metabolic and physiological research, this peptide continues to be an important tool for scientists investigating complex biological pathways

doi: 10.1016/j.biopha.2020.111202 197 TangRXuJZhangBLiuJLiangCHuaJet al

The major esterase enzymes responsible for hydrolyzing aspirin include carboxypeptidase in the liver, pseudocholinesterase in the plasma, and acetylhydrolase I, an intracellular enzyme found in erythrocytes (Ornelas et al, 2017)

In pathological RA conditions, a malfunction of p53 results in heightened activation of the PI3K/AKT pathway [76]

Additionally, postoperative pain can lead to gut microbiota dysbiosis, as the stress and inflammatory responses triggered by pain may disrupt the delicate balance of gut microbiota (Pusceddu and Gareau, 2018)