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The neurological phenotype of FRDA includes cerebellar atrophy in the dentate nucleus, the dorsal root ganglia become smaller, reduction in the spinal cord diameter, and loss of corticospinal and spinocerebellar tracts (Koeppen, 2011

[52] Joshi RP, Negi G, Kumar A, et al

Notably, no studies to date have specifically tested this hypothesis in patients with Hashimotos thyroiditis, limiting the generalisability of existing evidence to this particular population

These water-soluble vitamins are essential for metabolism, energy production, and cell function, including brain, heart, and immune system health

The findings provide valuable insights to optimize metformins therapeutic application in PCOS treatment, enabling safer pharmacologic management and improved patient prognoses