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Description

Peroxidation of lipids disturbs membrane organization, causing functional loss of proteins and DNA, and are found elevated in PD patients where lipid peroxidation adducts contribute to early demise of the SNpc neurons

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Available at: Copyright 2015

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System X c is a membrane-bound amino acid antiporter composed of Solute Carrier Family 7 Member 11 (SLC7A11) and Solute Carrier Family 3 Member 2 (SLC3A2)

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This is exacerbated by nutrient deficiencies, such as folate and vitamin B12, which are necessary for generating methionine

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