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doi:10.1016/j.fct.2021.112090 Hyson DA

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NNMT methylates nicotinamide to produce 1-methylnicotinamide (1-MNA), consuming SAMe and depleting cellular NAD+ pools

While these findings suggest potent fungicidal activity, the study represents a preclinical investigation, and further validation in larger, clinically relevant models are required to establish therapeutic relevance

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