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PLoS One 16, e0260633 (2021), Application(s): High-Content Imager

10.1021/acsnano.2c09593 42 HuangL.LiuG

Furthermore, to robustly quantify the transcriptomic similarity between tumor cells and myeloid cells, we calculated at single cell resolution multiple metrics, including Manhattan and Euclidean distance metrics, the Cosine and Pearson correlation-based directional similarity metrics, as well as the Phi and Bray-Curtis proportionality and compositional dissimilarity metrics 22,23

Therefore, therapeutic strategies that manipulate ROS levels, either by increasing oxidative stress to promote cell death or by targeting antioxidant pathways to inhibit tumor growth, are being explored 118

Birth Defects Research 114:551558 Keen JH, Habig W, Jakoby W (1976) Mechanism for the several activities of the glutathione S-transferases