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For example, in AD research, an FRG signature composed of genes such as DNA damage inducible transcript 4, mucin 1 and CD44 was found to not only distinguish patients with AD from healthy controls but also to predict disease severity and immune cell infiltration in the brain (43)

On the contrary, Acetyl-CoA is an activator of pyruvate carboxylase, thus promoting the TCA flux or the gluconeogenesis (Pietrocola et al., 2015)

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Noradrenaline axon terminals in adult rat neocortex: An immunocytochemical analysis in serial thin sections

Kojima, Masayasu, Hosoda, Hiroshi, Date, Yasuhiko, Nakazato, Mitsunobu, Matsuo, Hiroaki, and Kangawa, Ken