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However, while these benefits are enticing, they must be weighed against potential risks, especially for those with existing kidney concerns

Cancer Cell 8 , 143153 (2005)

It influences various aspects of cell cycle progression and is modulated by both autocrine and paracrine mechanisms

Thus, excessive CB1 activation with exogenous THC may lead to NMDAR hypofunction which in turn downregulates genes involved in synthesis, recycling and utilization of GSH in developing neurons, promoting oxidative stress