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The genes for inhibitors of the cell cycle (CDKN1, CDKN4D and ATM) are induced, whereas cyclins (proliferating cell nuclear antigen (PCNA), cyclin A, cyclin D1 and cyclin K) are downregulated during the period from 6 to 20 h [14]

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GSCs, as a highly specialized population of stem cells, play a crucial role in the progression and recurrence of GBM due to their ability to self-renew and continuously generate new tumor cells [152]

6.6%, respectively)