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[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Wei H., Zhu Y., Wang T., Zhang X., Zhang K., Zhang Z

Supporting Normal Metabolism

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(2016) identified metabolic features consistent with impaired one-carbon metabolism in chronic fatigue syndrome populations Methylated nutrient supplementation (methylfolate, methylcobalamin) is not universally appropriate and requires individualised clinical assessment What Is Methylation and Why It Matters Methylation is a fundamental biochemical process involving the transfer of a methyl group (CH3), occurring billions of times per second in every cell of the body