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It's "copper." Copper peptides derive their name from the element copper, which plays a crucial role in their function

Dietary glutamate (Glu), an excitatory neurotransmitter, permeates CVOs and overwhelms inhibitory GABA neurotransmission, impeding release of specific hypothalamic hormones, including those causing low cortisol, low aldosterone, and low ADH with subsequent hypovolemia

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In addition, as SMAD3 expression was low in LUHMES cells and its knockdown did not yield observable phenotypic changes such as protection against aSyn-induced toxicity (Fig