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However, when produced in excess, ROS can overwhelm cellular antioxidant defenses, leading to oxidative stress and the disruption of essential biomolecules, including nucleic acids, proteins, and membrane lipids

C 38 H 44 O 8 ) is recognized as the primary bioactive compound present in gamboge resin, possesses extensive anticancer potential, and is regarded as a promising broad-spectrum anticancer agent [21]

Fluorescent heme degradation products are biomarkers of oxidative stress and linked to impaired membrane integrity in avian red blood cells

Clin Cancer Res 20:43024313 Trachootham D, Alexandre J, Huang P (2009) Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach

Increases sensitivity to the sun Although rare, some people may develop allergic reactions to Kojic Acid