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The substantial weight reduction observed with tirzepatide monotherapy (15-21% body weight in clinical trials) suggests that any perceived benefits likely reflect tirzepatide's pharmacological effects rather than synergistic action

VEGF Upregulation AHK-Cu has also been associated with increased VEGF (vascular endothelial growth factor) production in scalp fibroblasts

The FDA requires extensive animal testing before human trials specifically because dangerous substances generally produce detectable harm in animal models

Which raises the harder question not just what works, but when something is ready to work

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