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It aids in transporting fatty acids into the mitochondria, promoting fat oxidation

Sierra-Filardi E, Vega MA, Snchez-Mateos P, Corb AL, Puig-Krger A (2010) Heme Oxygenase-1 expression in M-CSF-polarized M2 macrophages contributes to LPS-induced IL-10 release

However, there are several risk factors that may increase the risk

The gut microbiome, as the second genome, plays an important role in dynamically integrating signals from the host and its environment, impacting both physiological homeostasis and disease emergence ( Changes in gut microbiota alter the production of gut metabolites and thus affect the development of CVDs ( Although the role of TMAO in CVDs is well established, detailed understanding of how TMAO regulates the development and progression of CVDs has yet to be elucidated

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