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Deficiency Risks and Who Is Most Affected Certain groups are at higher risk of deficiency, including: Vegetarians and vegans Adults over 50 with reduced stomach acid Patients with gut disorders such as Crohns or celiac disease Those taking long-term acid-reducing medications Symptoms of deficiency can include fatigue, pale skin, memory loss, depression, numbness, or tingling sensations

[ [PMID: 33486974] [ [PMID: 29402234] [PMID: 11989457] et al

Patients should seek urgent medical advice for severe abdominal pain, persistent vomiting, or signs of pancreatitis or gallbladder disease

Your home refrigerator should maintain this range consistentlycheck it with a thermometer if you're uncertain

Theres yet to be a firmly established causation between vitamin B-12 deficiency and depression, but there is growing evidence that low B-12 levels may contribute to depressive symptoms, especially in older adults or those with other risk factors