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DEMETER2 (for RNAi) and CERES (for CRISPR) scores express how lethal is a knockdown or knockout, with highly negative values indicating stronger dependency of that gene

Cited 2/3/16

After the model was expanded to include GS-H 2 Q adduct formation as a function of its reduction potential, it was then combined with the Reed glutathione model 21 in order to simulate how the quinone redox-metabolism of doxorubicin influenced the glutathione metabolism

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