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being the major increase in the GPx enzyme (approximately at 190 %), followed by GST enzyme (approximately at 170 %), GSH (approximately at 160 %), and finally GR enzyme (approximately at 140 %)

Thus, one might propose that electrophilic species which target glutathione potently, are likely to be better tolerated than those which are not quenched by an equivalently large endogenous pool of protective nucleophiles