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When collagen breaks down, fragments of it called matrikines bind to fibroblast receptors and trigger new collagen production as a repair signal

For many in their 40s and 50s, the aggressive exfoliation of retinol can lead to "Inflammaging" a state of chronic irritation that can actually accelerate the breakdown of collagen

[DOI] [PubMed] [Google Scholar] 17.Swaim S

Beyond its ability to stimulate regeneration of skin, hair follicles, stomach and intestinal linings, and boney tissue, GHK-Cu strongly impacts gene expression relevant to nervous system health and function and may lessen the rate of cognitive decline [12]