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What they found: Dose-dependent stimulation of type II collagen (up to 2.5 baseline at 100 nM) Stimulation of aggrecan (up to 1.8 baseline) Inhibition of MMP-13 by ~40 % Partial protection against IL-1-induced matrix degradation Why it matters: It opened a completely new research area for AOD-9604 beyond lipolysis

Measurement of SIRT1 and SIRT3 activities in cultured cells and in mouse tissues Cultured CHO-mCD38 cells, and liver and spleen from treated mice were harvested and homogenized in M-PER Mammalian Protein extraction buffer on ice as described previously 25

Potential Benefits of AOD-9604 While AOD-9604 is still under investigation, various users and some preliminary research point to several possible benefits: Weight Management Support: Its main claim to fame is fat metabolism enhancement, which could make it helpful for individuals aiming to shed stubborn pounds

Copper supports iron metabolism, connective tissue, and nervous system function