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DOI: Received: Accepted: Published: Publisher Name: Springer, Cham Print ISBN: 978-3-030-71519-9 Online ISBN: 978-3-030-71519-9 eBook Packages: Living Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

Both systems appear to mediate similar physiological effects

The combined activation of all three pathways is hypothesised to produce more pronounced and sustained weight reduction, though the long-term clinical implications of each receptor's contribution remain to be fully established

Hence, FOXO-DRI protein or other modified alternatives may be valuable in researching certain neurodegenerative conditions by substituting the absence of native FOXO proteins

The N-Methyl-D-aspartate receptors (NMDAR), ionotropic glutamate receptor, are essential for processes like learning and memory