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By fitting the plasma concentrations to a non-compartmental PK model 34 , we found that the IgG1-REW variants were present at higher concentrations in plasma over time (AUC) compared to WT, had slower clearance, longer mean residence time and lower volume of distribution at steady state (Table S4)

Wiley, pp 398427

N-acetyl cysteine dosing for liver support typically ranges from 600mg to 1800mg daily

Dynamic simulations on the arachidonic acid metabolic network