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This approach not only induces cuproptosis but also increases PD-L1 expression, transforming cold tumors into hot tumors that respond to immunotherapy, significantly inhibiting tumor growth and activating a systemic anti-tumor immune response

Acknowledgments We thank Figdraw ( for expert assistance in the pattern drawing

Le Henaff C, Mansouri R, Modrowski D et al (2015) Increased NF-B activity and decreased Wnt/-catenin signaling mediate reduced osteoblast differentiation and function in F508 cystic fibrosis transmembrane conductance regulator (CFTR) mice

To test the direction of the main effect of group, post hoc two-sample t -test was used to detect rs-fMRI differences between NAC and CN groups at baseline and follow-up

10.1111/j.1600-065X.2012.01158.x 272 RebsamenM.PochiniL.StasykT.De AraujoM