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For example, DMOCPTL regulates EGR1 in TNBC cells and induces GPX4 ubiquitination to reduce EGR4 protein levels, thereby regulating mitochondria-mediated apoptosis [80]

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A study comparing individuals with insomnia to healthy sleepers found significantly lower glutathione peroxidase activity in the insomnia group

These differences might be due to intrinsic biological characteristics of each cell line, which may confer differential properties to tumor cells in response to pharmacological challenges in specific manners [43]