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Description

Siener, R., Machaka, I., Alteheld, B., Bitterlich, N., & Metzner, C

NOD2 regulates NF-B/MAPK through the receptor-interacting serine/threonine-protein kinase 2 (RIPK2)- X-linked inhibitor of apoptosis protein(XIAP) axis, and drugs targeting this interaction have shown potential for alleviation [374, 375]

doi: 10.1016/j.coi.2007.05.004 79 ReedJC

Methods Enzymol 352: 258268

Mitochondrial damage and ROS accumulation leads to DA neuron loss, it was believed that KD conferred neuroprotection through its potential as a substrate for energy substitution