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5-Amino-1MQ is a selective small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) an enzyme implicated in adipocyte energy storage, NAD+ metabolism, and one-carbon metabolic signalling

This condition can be triggered by factors such as excessive alcohol consumption, prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs), or infection with Helicobacter pylori bacteria