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Increased VEGFA promotes the formation of senile cataracts, neovascular and nonexudative agerelated macular degeneration

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However, bacterial resistance to antibiotics, caused by excessive usage and misuse of these life-saving drugs over the last few decades, has led us to a significant public health crisis that develops and spreads at an alarming rate [1,2,3]

However, the citral chemotype is stressful for silver catfish because there was an up regulation of s lc6a2 , crh , 20-hydroxysteroid dehydrogenase ( hsd20b ) and heat shock proteins 70 member 12 ( hspa12a ) and heat shock protein 90 ( hsp90 ) (Souza et al., 2019

doi: 10.1016/j.sjbs.2018.07.005 16