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doi: 10.1111/j.1365-2826.2008.01805.x 8 TalpurHSChandioIBBrohiRDWorkuTRehmanZUBhattaraiDet al

Nowadays, metabolomics is recognized as a powerful tool for assessing the positive and negative effects of drugs under different exposure conditions ( Furthermore, the combination of metabolomics with in vitro models represents a great step forward in the use of human-relevant non-animal alternatives in toxicology

Tesamorelin is the stronger-evidence molecule: it is supported by multiple randomized, double-blind, placebo-controlled Phase 3 human trials of roughly 400 patients each, and it carries a current U.S

Moreover, the contribution of presynaptic EAAT2 to the glutamate uptake has been acknowledged in hippocampal neurons (Furness et al., 2008)

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