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Once reconstituted, MOTS-c must be stored at 28C and used within 28 days to prevent degradation

Building on this understanding, recent advances in nanomedicine have leveraged these principles to refine ICD-based in situ cancer vaccines, enhancing antigenicity and adjuvanticity while overcoming key barriers in conventional approaches

The RPE has a high-level expression of cholesterol homeostasis-associated genes, including HMGCR, SCREBP2, SCAP, NR1H3, CYP27A1, CYP46A1, ABCA1, and ABCG1 (Zheng et al., 2015