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Therefore, investigating the serum B12 levels before premedication and FA levels before pemetrexed administration may help predict hematological AEs

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It will depend on the ability to connect multiple sources of evidence, including: Clinical trial data Real-world clinical data Patient-reported outcomes Biomarker and genomic information Healthcare utilization data Digital health technologies The goal is not to replace randomized clinical trials but to complement them, creating a more complete picture of how therapies perform in real-world healthcare settings

The next day, cells were treated with or without 500 M NaOX for approximately 18 h