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Heesun Chung, BS, PhD

Melanotic macule of the oral mucosa

The -MSH acts on specialised skin cells responsible for producing pigment

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These estimates underscore the argument that prophylactic excision of dysplastic nevi is unlikely to be cost effective and might, in addition, give patients a false sense of security, since an increased risk of melanoma may remain after these nevi have been removed. (Naeyert, N Engl J Med 2003;349:2233-40.) She further states that prophylactic excision is not warranted for lesions diagnosed clinically as dysplastic nevi, since the probability that a single lesion will develop into melanoma is very low and since excision does not clearly reduce the overall risk of melanoma. However, excision with 2 mm margins is always indicated where melanoma is suspected by a clinicians inspection