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A common combination protocol: Epitalon: 10-day injection cycle (1 to 2 mg daily) every 4 to 6 months Pinealon: Daily sublingual or injection between Epitalon cycles DSIP: Added as needed for acute sleep difficulties or during high-stress periods The stacking approach allows each peptide to address a different aspect of sleep dysfunction

Its sequence is Glu-Asp-Arg, which is why it is also called the EDR peptide

Within minutes, the vast majority is degraded and cleared

The starting point for this study was a recently published study (Benoist et al., 2011) that determined that the information in Nle 1 -AngIV critical to its procognitive activity resided in its three to four N-terminal amino acids