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Meperidine (initial dose 2550 mg i.v.) has shorter half-life but puts patients are at higher risk of metabolite accumulation (neuromuscular side effects) when repeated doses accumulate

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Together, oxidative stress and excitotoxicity form a dual mechanism that underpins the neural damage caused by N 2 O exposure

Ellagic acid protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by modulating the PI3K/Akt/eNOS pathway

These results revealed previously unknown metabolic phenotypes, identified new developmental states of the metabolic correlation network, and underscored the role of mitochondrial functional changes, purine metabolism, and purinergic signaling in autism spectrum disorder