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Structure of the human FOXO4-DBD-DNA complex at 1.9 resolution reveals new details of FOXO binding to the DNA

Meanwhile, NNMTi preserves lean body mass: it reduces fat accumulation without causing muscle loss, which is crucial for maintaining basal metabolism and preventing weight regain after dieting.These in vivo findings fully validate the efficacy and safety of NNMTi in obesity intervention, laying a solid foundation for its subsequent clinical research and drug development

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31, it is conducted by the synergy effect of activated carbon adsorption and biodegradation of O 3 -BAC