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In addition, during copper removal treatment, a 46-year-old male patient with cirrhosis developed hepatocellular carcinoma, and a 38-year-old woman developed breast cancer, indicating that copper deposition does not protect against the occurrence of cancer

In addition to neural connections, the central clock system also synchronizes the circadian rhythms of the peripheral clock system through hormones or factors, such as arginine vasopressin (AVP) and tumor necrosis factor (TNF) ( FIGURE 1 The clock system mainly regulates metabolism in the following three ways

doi: 10.3390/nu14214476

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