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doi: 10.1073/pnas.1911612116 57 TremelSOhashiYMoradoDRBertramJPerisicOBrandtLTLet al

Tivantinib (ARQ 197) is a staurosporine derivative and it represents the first non-ATP-competitive c-Met inhibitor that binds to the dephosphorylated c-Met kinase in vitro