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In animal models, increased permeability of the blood-brain barrier (BBB) to pro-inflammatory cytokines, chemokines such as IL-1 and TNF- and the direct leak of bacterial products such as lipopolysaccharide (LPS) and bacterial lipopeptide (BLP), that activate microglia to release inflammatory mediators, induce preterm brain damage

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doi: 10.3389/fendo.2022.1042511 92 KyriakouAPatsatsiASotiriadisDGoulisDG

The micellar core consists of the hydrophobic blocks and the shell region consists of the hydrophilic blocks (53)