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Treatment Protocol for Trigeminal Neuralgia Because of the off-label nature of onabotulinumtoxinA treatment for TN, no standardization of injection sites exists

Subjects were initially treated for 6 months of on-demand therapy and then randomized to 12 months of either a standard prophylaxis regimen (20 to 40 IU/kg every 48 hours) or PK-driven prophylaxis regimen (20 to 80 IU/kg every 72 hours)

Femoral Notch Width A narrower femoral notch has been associated with a higher risk of ACL injury

The medium was removed, and 0.4 mL of MTT solution (Sigma) was added to each well and incubated for another 4 h