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Absent the unlikely situation that the additives would eliminate tobacco smoke's genotoxicity and mutagenicity, the failure to find increased toxicity associated with the additives does not support the conclusion that in vitro mutagenicity and cytotoxicity of the cigarette smoke were not increased by the addition of the ingredients [17]

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Gradual reduction: If youre using NRT intending to quit nicotine altogether, consider a gradual reduction approach