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Upon withdrawal, these issues can persist, further compounding stress levels and triggering elevated cortisola primary stress hormone linked to increased cravings, irritability, and relapse risk

Tobacco and cancer were not yet linked

The size of the non-tobacco flavored market differs by state (figures in Table 1), and the estimates reflect these differences

High Excise Taxes: State-level taxes make the retail price of imported luxury tobacco significantly higher than in domestic markets