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[9] The World Health Organization estimates that, annually, more than 7 million people die from tobacco-related causes, including 1 } : CS1 maint: DOI inactive as of July 2026 (link) Endocrine

Significant increases in daily vaping were also seen among males aged between 25 and 49, and among women aged 25 to 59see Figure 18.3.4

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The major risks include: Ectopic pregnancy (when a fertilised egg implants outside the uterus) Miscarriage (spontaneous abortion) Intrauterine growth restriction (IUGR) Placenta previa (a condition where the placenta covers the cervix, leading to complications) Premature rupture of membranes (PROM) Preterm birth Low birth weight Perinatal mortality (death of the baby around the time of birth) Additionally, studies suggest that maternal smoking during pregnancy may negatively impact the sperm quality of male offspring later in life