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It is naturally produced in plants of the nightshade family, but apart from tobacco, the contents are low

At the same time, it has sometimes disregarded, or even cut off, studies of its own that implicated smoking as a health hazard.[5] In February 1994, FDA Commissioner David Kessler announced evidence that tobacco manufacturers were deliberately manipulating the nicotine content in cigarettes and, as a result, the FDA was prepared to consider regulating tobacco products, a major policy shift

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