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Primary pollutants can then react in the air to form secondary pollutants

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[193] On average a regular cigarette contains 628 mg of nicotine or the user will inhale about 1.1 to 1.8 mg of nicotine if just a portion is used

"The reliance by PHE on work that the authors themselves accept is methodologically weak, and which is made all the more perilous by the declared conflicts of interest surrounding its funding, raises serious questions not only about the conclusions of the PHE report, but also about the quality of the agency's peer review process." (E-cigarettes: Public Health England's evidence-based confusion)(iii)

But, "that doesn't mean they're going to win." Kaelan Hollon, a spokeswoman for Reynolds American, the tobacco company that led the 2011 suit, says they are "carefully reviewing the FDA's latest proposal for graphic warnings." "We firmly support public awareness of the harms of smoking cigarettes," she says, "but the manner in which those messages are delivered to the public cannot run afoul of the First Amendment protections that apply to all speakers, including cigarette manufacturers."