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People with a history of severe allergy to bee stings are at risk of developing a life-threatening reaction to a single sting, as they might with a sting by a domestic honeybee

Low-dose ketamine-assisted therapy, currently studied in Phase 2 and 3 trials for AUD, targets NMDA glutamate receptor dysregulation, the same receptor system that drives alcohol withdrawal kindling, and has shown efficacy in reducing craving and relapse in early trials

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For a long time, people who used tobacco products could not quit because there was no adequate replacement

Other enzymes such as CYP2C19, CYP3A4, CYP2D6 and UGT 1A3/4 play a minor role in the metabolic pathway