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SKU: 88910744549
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C.SilvaF

U.SammantasingharA.KausarF.FarooqiM

Overproduction of DPT triggers ROS-induced upregulation of PARP-1, which promotes apoptosis-inducing factor (AIF) translocation into the nucleus, causing parthanatos in glioma cells (Ma et al., 2016)

doi: 10.1016/j.bcp.2024.116717

There have been many studies involving characterization of these enzymes as well as overexpressing these enzymes for engineering stress tolerance though much is not known about the comparative role of each of these genes in MG detoxification